Liquidambaric lactone

Research use only, not for human use.

Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity.

Liquidambaric lactone is a compound isolated from Euonymus grandiflorus Wall.Liquidambaric lactone may have inhibitory HIV-1 reverse transcriptase activity.Among the 25 fractions obtained from the alcohol extractive of the roots of Lantana camara L.(Verbenaceae) by silica gel column chromatography,three fractions demonstrated inhibitory HIV-1 reverse transcriptase activity.Furthermore,six pentacyclic triterpenes were isolated by reduced pressure column chromatography and identified as oleanonic acid(1),Liquidambaric lactone(2),lantadene A(3),lantadene B(4),oleanolic acid(5),and 25-hydroxy-oleanolic acid(6) by spectral analysis. Compounds 2 and 6 were reported firstly in the plants of Verbenaceae family,and the structure of 6 was confirmed firstly by X-ray crystallography.

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Microbiology/Virology

HIV

HIV-1

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185051-75-6

468.67

C30H44O4

>98% (HPLC)

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C[C@]1([C@@]2(CC[C@@]3([H])C4(C)C)C)[C@@]([C@@H](O5)[C@@H]5[C@]2([H])[C@]3(CCC4=O)C)(OC6=O)[C@@](CC(C)(C)CC7)([H])[C@]67CC1

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(-20℃)

With Ice Pack

≥ 2 years